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Phenylpropaniods are organic compounds characterized by having an aromatic ring and a three-carbon propene tail. Polyketides are compounds characterized by having two or more carbonyl functional groups connected with a single carbon atom.
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Inhibits CK2 activity in the renal cortex with an IC50 value of 30 µM; potent inhibitor of NO and PGE2 biosynthesis by reducing iNOS and COX-2 expression
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A fluorescent probe for detection of peroxynitrite; a more soluble form of CBA; can be used to detect peroxynitrite, hypochlorous acid, and hydrogen peroxide; COH displays ex/em = 332/470 nm, respectively
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Coumarin 314 is a fluorescent dye that exhibits intense absorption in the visible region and pronounced solvent-dependent spectral behavior. It is used as a visible-absorbing fluorophore for photophysical studies, fluorescence labeling, and materials research, and is supplied with analytical documentation for research use.
Intense absorption in the visible region.
Pronounced solvent-dependent spectral behavior.
High stated purity of 98.0%.
Available in small research quantities (100 mg, 250 mg, 500 mg; larger sizes by request).
Manufacturer provides SDS, COA, and a data sheet for each batch.
Suitable for fluorescence labeling and photophysical studies.
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A polymethoxylated flavone isolated from citrus peels; inhibits signaling in cancer cells, reducing ERK signaling in T47D breast cancer cells (IC50 ~3 μM)
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A flavonoid compound that acts as a powerful antioxidant; inhibits TBARS formation with an IC50 value of 6.34 µM; blocks oxLDL uptake by U937-derived macrophages at 20 µM; demonstrates potent chemopreventative potential by binding JAK1/STAT3 to inhibit neoplastic transformation of murine JB6 Pt cells
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A flavonoid compound that acts as a powerful antioxidant; inhibits TBARS formation with an IC50 value of 6.34 µM; blocks oxLDL uptake by U937-derived macrophages at 20 µM; demonstrates potent chemopreventative potential by binding JAK1/STAT3 to inhibit neoplastic transformation of murine JB6 Pt cells
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A potent antagonist of the TXA2 receptor, blocking specific binding of U-46619 to platelets with an IC50 value of 7.4 nM and platelet aggregation induced by U-44069 with an IC50 value of 350 nM; commonly used to study the roles of the TP receptor in animal airways and in tissue samples
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Dibenzoylmethane is a minor ingredient found in licorice that functions as a Keap1-Nrf2 activator. It is known to prevent various cancers and oxidative damage. As an analog of curcumin, it facilitates dissociation from Keap1, leading to the nuclear translocation of Nrf2.
Activates Nrf2
Prevents various cancers and oxidative damage
Increases mRNA level of HO-1 in HepG2 cells
Induces HO-1 and Nrf2 protein expression
Increases phosphorylated protein levels of Erk1/2, p38MAPK, JNK, AMPK, and Akt in HepG2 cells
Reduces area and severity of necrosis and leukocyte infiltration
Protects against CCl4-induced liver damage
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7-Methoxycoumarin-3-carboxylic acid is a coumarin-based fluorescent dye used for labeling peptides and synthesizing fluorescent probes. It provides ultraviolet excitation and blue emission suitable for fluorescence assays, probe development, and HPLC derivatization. The material is supplied at research-grade purity for laboratory use.
High purity (97.0%).
Excitation 345 nm, emission 450 nm.
Molecular weight 220.18 g/mol.
Chemical formula C11H8O5.
Available in multiple pack sizes including 25 g.
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Zearalenone is a fungal mycotoxin supplied as a ready-to-use 10 mM solution in DMSO for research and analytical assays. The solution offers consistent concentration for assay setup, and is provided at high chemical purity for reliable results.
Ready-to-use 10 mM solution in DMSO
Convenient 1 mL vial for small-scale assays
High purity for analytical reproducibility
Accurate concentration to simplify assay setup
Intended for research and analytical applications only
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